Ac₄GlcNAlk

Name: Ac 4 GlcNAlk
Brand: Tocris Bioscience
SKU: 7750

Tocris Bioscience, part of Bio-Techne | Catalog # 7750

COA / SDS

Metabolic chemical reporter for studying glycosylation and glycoproteins

Key Product Details

Description:	Metabolic chemical reporter for studying glycosylation and glycoproteins
Chemical Name:	2-Deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-D-glucopyranose-1,3,4,6-tetraacetate
Purity:	≥95% (HPLC)
Molecular Weight:	427.41

View Full Technical Details for Ac₄GlcNAlk

Technical Data
Citations

Biological Activity for Ac₄GlcNAlk

Ac₄GlcNAlk is a metabolic chemical reporter (MCR) for studying cell surface glycosylation. It is used for identification of O-GlcNAc modified proteins. In cells expressing the engineered pyrophosphorylase, mut-AGX1, Ac₄GlcNAlk is efficiently converted into UDP-GlcNAlk which is incorporated into GlcNAlk-containing glycoproteins.

Technical Data for Ac₄GlcNAlk

M. Wt	427.41
Formula	C₁₉H₂₅NO₁₀
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	1361993-37-4
PubChem ID	101797984
InChi Key	PODQGPKRSTUNAT-ULAPBGCESA-N
Smiles	CC(OC[C@H]1OC([C@@H]([C@H]([C@@H]1OC(C)=O)OC(C)=O)NC(CCC#C)=O)OC(C)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Ac₄GlcNAlk

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	42.74	100

Preparing Stock Solutions for Ac₄GlcNAlk

The following data is based on the product molecular weight 427.41.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.34 mL	11.70 mL	23.40 mL
5 mM	0.47 mL	2.34 mL	4.68 mL
10 mM	0.23 mL	1.17 mL	2.34 mL
50 mM	0.05 mL	0.23 mL	0.47 mL

Molarity Calculator

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Reconstitution Calculator

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References for Ac₄GlcNAlk

References are publications that support the biological activity of the product.

Cioce Optimization of metabolic oligosaccharide engineering with Ac₄GalNAlk and Ac₄GlcNAlk by an engineered pyrophosphorylase. ACS Chem.Biol. 2021 PMID: 33835779

Ac₄GlcNAlk

Tocris Bioscience, part of Bio-Techne | Catalog # 7750

Key Product Details

Biological Activity for Ac₄GlcNAlk

Technical Data for Ac₄GlcNAlk

Solubility for Ac₄GlcNAlk

Preparing Stock Solutions for Ac₄GlcNAlk

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Ac₄GlcNAlk

Product Documents for Ac₄GlcNAlk

COA

Certificate of Analysis

SDS

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Ac4GlcNAlk

Tocris Bioscience, part of Bio-Techne | Catalog # 7750

Key Product Details

Biological Activity for Ac4GlcNAlk

Technical Data for Ac4GlcNAlk

Solubility for Ac4GlcNAlk

Preparing Stock Solutions for Ac4GlcNAlk

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Ac4GlcNAlk

Product Documents for Ac4GlcNAlk

COA

Certificate of Analysis

SDS

Ac₄GlcNAlk

Biological Activity for Ac₄GlcNAlk

Technical Data for Ac₄GlcNAlk

Solubility for Ac₄GlcNAlk

Preparing Stock Solutions for Ac₄GlcNAlk

References for Ac₄GlcNAlk

Product Documents for Ac₄GlcNAlk