Acarbose

Name: Acarbose
Brand: Tocris Bioscience
SKU: 2673

Tocris Bioscience, part of Bio-Techne | Catalog # 2673

Citations (5)

COA / SDS

Glucosidase α inhibitor (intestinal)

Key Product Details

Chemical Name:	O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-Glucose
Molecular Weight:	645.25 kDa

View Full Technical Details for Acarbose

Technical Data
Citations

Biological Activity for Acarbose

Acarbose is an inhibitor of intestinal α-glucosidase (IC₅₀ = 11 nM). Antidiabetic; inhibits the hydrolysis of complex carbohydrates.

Technical Data for Acarbose

M. Wt	645.25 kDa
Formula	C₂₅H₄₃NO₁₈
Storage	Desiccate at RT
CAS Number	56180-94-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Acarbose

Solubility

Soluble Soluble to 100 mM in water and to 100 mM in DMSO

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References for Acarbose

References are publications that support the biological activity of the product.

Balfour and McTavish Acarbose: an update of its pharmacology and therapeutic use in diabetes mellitus. Drugs, 1993;46:1025 PMID: 7510610
Oki et al. Evaluation of alpha-glucosidase inhibition by using an immobilized assay system. Biol.Pharm.Bull., 2000;23:1084 PMID: 10993209
Krause et al. Inhibition of disaccharide digestion in rat intestine by the alpha-glucosidase inhibitor aca. (BAY g 5421). Digestion, 1982;23:232 PMID: 6754513