Aspirin

Name: Aspirin
Brand: Tocris Bioscience
SKU: 4092

Tocris Bioscience, part of Bio-Techne | Catalog # 4092

Citations (7)

COA / SDS

Cyclooxygenase inhibitor; NSAID

Key Product Details

Description:	Cyclooxygenase inhibitor; NSAID
Chemical Name:	2-Acetoxybenzoic acid
Purity:	≥99% (HPLC)
Molecular Weight:	180.16

View Full Technical Details for Aspirin

Technical Data
Citations

Biological Activity for Aspirin

Aspirin is an inhibitor of cyclooxygenase (COX)-1. Blocks the production of prostaglandins and thromboxanes. Exhibits antiplatelet and antithrombotic activities. Displays anticancer effects in some solid tumors. One of the first described NSAID drugs.

Compound Libraries for Aspirin

Aspirin is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.

Technical Data for Aspirin

M. Wt	180.16
Formula	C₉H₈O₄
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	50-78-2
PubChem ID	2244
InChi Key	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
Smiles	CC(OC1=C(C(O)=O)C=CC=C1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Aspirin

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	1.8	10
	DMSO	18.02	100

Preparing Stock Solutions for Aspirin

The following data is based on the product molecular weight 180.16.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.55 mL	27.75 mL	55.51 mL
5 mM	1.11 mL	5.55 mL	11.10 mL
10 mM	0.56 mL	2.78 mL	5.55 mL
50 mM	0.11 mL	0.56 mL	1.11 mL

Molarity Calculator

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Reconstitution Calculator

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References for Aspirin

References are publications that support the biological activity of the product.

Wu Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells. Proc.Natl.Acad.Sci.U.S.A. 1991 PMID: 1900943
Baron Aspirin and cancer. Preventative Medicine 1995 PMID: 7597012
Schror Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis. Semin.Thromb.Hemost. 1997 PMID: 9263351

Product Documents for Aspirin

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

SDS

⚠ WARNING: This product can expose you to chemicals including Aspirin (NOTE: It is especially important not to use aspirin during the last three months of pregnancy, unless specifically directed to do so by a physician because it may cause problems in the unborn child or complications during delivery.), which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov