AZD 8055

Name: AZD 8055
Brand: Tocris Bioscience
SKU: 7840

Tocris Bioscience, part of Bio-Techne | Catalog # 7840

Citations (4)

COA / SDS

Highly potent and selective mTOR inhibitor

Key Product Details

Chemical Name:	5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
Purity:	≥98%

View Full Technical Details for AZD 8055

Technical Data
Citations

Biological Activity for AZD 8055

AZD 8055 is a highly potent, selective and ATP-competitive mTOR inhibitor (IC₅₀ = 0.8 nM). Inhibits growth and induces autophagy in a range of cancer cell lines and xenografts, including NSCLC and glioblastoma (IC₅₀ values are 20, 50 and 53 nM in H838, A549 and U87MG cell lines, respectively). Orally bioavailable.

Technical Data for AZD 8055

Formula	C₂₅H₃₁N₅O₄
Storage	Store at -20°C
Purity	≥98%
CAS Number	1009298-09-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for AZD 8055

Solubility

Soluble Soluble to 100 mM in DMSO and to 20 mM in ethanol

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Product Documents for AZD 8055

COA

Certificate of Analysis

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