Bay 11-7085

Biological Activity for Bay 11-7085

Technical Data for Bay 11-7085

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Bay 11-7085

References for Bay 11-7085

References are publications that support the biological activity of the product.

• Clark P, Kim R, Pober J, Kluger M Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-kappaB-dependent phases. PLoS ONE, 2015;10(3):e0120075. 2015 PMID: 25816133
• N Li, H Hui, B Bray, GM Gonzalez, M Zeller, KG Anderson, R Knight, D Smith, Y Wang, AF Carlin, TM Rana METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection Cell Reports, 2021;35(6):109091. 2021 PMID: 33961823
• Balzarolo M, Karrich J, Engels S, Blom B, Medema J, Wolkers M The transcriptional regulator NAB2 reveals a two-step induction of TRAIL in activated plasmacytoid DCs. Eur J Immunol, 2012;42(11):3019-27. 2012 PMID: 22806638
• Kwon O, Valdez J, Zhang L, Zhang B, Wei X, Su Q, Ittmann M, Creighton C, Xin L Increased Notch signalling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells. Nat Commun, 2014;5(0):4416. 2014 PMID: 25048699
• Hu et al. An IκBα inhibitor causes leukemia cell death through a p38 MAP kinase-dependent, NF-κB-independent mechanism. Cancer Res., 2001;61:6290 PMID: 11507084
• Scaife et al. Nuclear factor κB inhibitors induce adhesion-dependent colon cancer apoptosis: implications for metastasis. Cancer Res., 2002;62:6870 PMID: 12460901
• Pierce et al. Novel inhibitors of cytokine-induced IkBa phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J.Biol.Chem., 1997;272:21096 PMID: 9261113