BW 373U86

Name: BW 373U86
Brand: Tocris Bioscience
SKU: 1663

Tocris Bioscience, part of Bio-Techne | Catalog # 1663

Citations (1)

COA / SDS

Potent, selective non-peptide δ agonist

Discontinued Product

1663 has been discontinued. View all delta Opioid Receptor Agonists products.

Key Product Details

Description:	Potent, selective non-peptide δ agonist
Chemical Name:	4-[(αR)-α-((2S,5R*)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl]-N,N-diethylbenzamide
Purity:	≥99% (HPLC)
Molecular Weight:	435.61

View Full Technical Details for BW 373U86

Technical Data
Citations

Biological Activity for BW 373U86

BW 373U86 is a potent, selective non-peptide δ-opioid receptor agonist. K_i values are 1.8, 15 and 34 nM for δ, μ and κ receptors respectively. Centrally active following systemic administration in vivo.

Licensing Information

Sold for research purposes under agreement from GlaxoSmithKline

Technical Data for BW 373U86

M. Wt	435.61
Formula	C₂₇H₃₇N₃O₂
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	155836-50-3
PubChem ID	119029
InChi Key	LBLDMHBSVIVJPM-YZIHRLCOSA-N
Smiles	O=C(N(CC)CC)C1=CC=C([C@@]([H])(N3C[C@@H](C)N(CC=C)C[C@@H]3C)C2=CC(O)=CC=C2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for BW 373U86

References are publications that support the biological activity of the product.

Chang A novel, potent and selective nonpeptidic delta opioid receptor agonist BW373U86. J.Pharmacol.Exp.Ther. 1993 PMID: 8246159
Dykstra A novel delta opioid agonist, BW373U86, in squirrel monkeys responding under a schedule of shock titration. J.Pharmacol.Exp.Ther. 1993 PMID: 8246162
Broom Comparison of receptor mechanisms and efficacy requirements for δ-agonist-induced convulsive activity and antinociception in mice. J.Pharmacol.Exp.Ther. 2002 PMID: 12388657