C 021 dihydrochloride

Name: C 021 dihydrochloride
Brand: Tocris Bioscience
SKU: 3581

Tocris Bioscience, part of Bio-Techne | Catalog # 3581

(1)

Citations (10)

COA / SDS

Potent CCR4 antagonist

Key Product Details

Chemical Name:	2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride
Purity:	≥99%
Molecular Weight:	540.57 kDa

View Full Technical Details for C 021 dihydrochloride

Technical Data
Citations / Reviews (1)

Biological Activity for C 021 dihydrochloride

C 021 dihydrochloride is a potent CCR4 chemokine receptor antagonist (IC₅₀ values are 0.14 and 0.039 μM for inhibition of chemotaxis in human and mouse respectively).

Technical Data for C 021 dihydrochloride

M. Wt	540.57 kDa
Formula	C₂₇H₄₁N₅O₂.2HCl
Storage	Desiccate at RT
Purity	≥99%
CAS Number	1784252-84-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for C 021 dihydrochloride

Solubility

Soluble Soluble to 50 mM in water and to 100 mM in DMSO

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References for C 021 dihydrochloride

References are publications that support the biological activity of the product.

Yokoyama et al. Potent and orally bioavailable CCR4 antagonists: synthesis and structure-activity relationship study of 2-aminoquinazolines. Bioorg.Med.Chem., 2009;17:64 PMID: 19081254