Camptothecin

Biological Activity for Camptothecin

Technical Data for Camptothecin

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Camptothecin

References for Camptothecin

References are publications that support the biological activity of the product.

• Fox JT, Sakamuru S, Huang R High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. 2012 PMID: 22431602
• Liu DNA topoisomerase poisons as antitumour drugs. Annu.Rev.Biochem, 1989;58:351 PMID: 2549853
• Hsiang et al. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J.Biol.Chem., 1985;260:14873 PMID: 2997227
• Pantazis et al. Camptothecin derivatives induce regression of human ovarian carcinomas grown in nude mice and distinguish between non-tumorigenic and tumorigenic cells in vitro. Int.J.Cancer, 1993;53:863 PMID: 8449612