Chem-CLIP control probe

Name: Chem-CLIP control probe
Brand: Tocris Bioscience
SKU: 7769

Tocris Bioscience, part of Bio-Techne | Catalog # 7769

COA / SDS

Control probe for Chem-CLIP experiments

Key Product Details

Description:	Control probe for Chem-CLIP experiments
Chemical Name:	3-(3-Butyn-1-yl)-N-propyl-3H-diazirine-3-propanamide
Purity:	≥95% (HPLC)
Molecular Weight:	207.28

View Full Technical Details for Chem-CLIP control probe

Technical Data
Citations

Biological Activity for Chem-CLIP control probe

Chem-CLIP (chemical cross-linking and isolation by pull-down) control probe is a control probe for Chem-CLIP experiments.

Technical Data for Chem-CLIP control probe

M. Wt	207.28
Formula	C₁₁H₁₇N₃O
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	2767983-73-1
PubChem ID	170526590
InChi Key	CYVAYGJWWZAPCE-UHFFFAOYSA-N
Smiles	O=C(CCC1(CCC#C)N=N1)NCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Chem-CLIP control probe

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	20.73	100

Preparing Stock Solutions for Chem-CLIP control probe

The following data is based on the product molecular weight 207.28.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.82 mL	24.12 mL	48.24 mL
5 mM	0.96 mL	4.82 mL	9.65 mL
10 mM	0.48 mL	2.41 mL	4.82 mL
50 mM	0.10 mL	0.48 mL	0.96 mL

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Reconstitution Calculator

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References for Chem-CLIP control probe

References are publications that support the biological activity of the product.

Tong Transcriptome-wide mapping of small-molecule RNA-binding sites in cells informs an isoform-specific degrader of QSOX1 mRNA. J.Am.Chem.Soc. 2023 PMID: 37058601
Bush Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models. Sci.Transl.Med. 2021 PMID: 34705518