Click N-Acetylmuramic acid - alkyne

Name: Click N -Acetylmuramic acid - alkyne
Brand: Tocris Bioscience
SKU: 6798

Tocris Bioscience, part of Bio-Techne | Catalog # 6798

COA / SDS

Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes

Key Product Details

Description:	Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes
Chemical Name:	(2R)-2-(((3R,4R,5S,6R)-2,5-dihydroxy-6-(hydroxymethyl)-3-(pent-4-ynamido)tetrahydro-2H-pyran-4-yl)oxy)propanoic acid
Purity:	≥95% (HPLC)
Molecular Weight:	331.32

View Full Technical Details for Click N-Acetylmuramic acid - alkyne

Technical Data
Citations

Biological Activity for Click N-Acetylmuramic acid - alkyne

Derivative of N-acetylmuramic acid (NAM) component of bacterial peptidoglycans. Incorporated into bacterial peptidoglycans during biosynthesis. Suitable for fluorescent labeling of peptidoglycans when 'click'-conjugated to a fluorescent dye.

Licensing Information

Sold under license from the University of Delaware

Technical Data for Click N-Acetylmuramic acid - alkyne

M. Wt	331.32
Formula	C₁₄H₂₁NO₈
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	2245794-65-2
PubChem ID	138991784
InChi Key	DLRFETWLAWCVSX-UWOBWZKWSA-N
Smiles	C[C@H](C(O)=O)O[C@H]1[C@@H]([C@H](OC([C@@H]1NC(CCC#C)=O)O)CO)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Click N-Acetylmuramic acid - alkyne

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	33.13	100

Preparing Stock Solutions for Click N-Acetylmuramic acid - alkyne

The following data is based on the product molecular weight 331.32.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.02 mL	15.09 mL	30.18 mL
5 mM	0.60 mL	3.02 mL	6.04 mL
10 mM	0.30 mL	1.51 mL	3.02 mL
50 mM	0.06 mL	0.30 mL	0.60 mL

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References for Click N-Acetylmuramic acid - alkyne

References are publications that support the biological activity of the product.

DeMeester Synthesis of functionalized N-Acetyl muramic acids to probe bacterial cell wall recycling and biosynthesis. J.Am.Chem.Soc 2018 PMID: 29986130
Liang Metabolic labelling of the carbohydrate core in bacterial peptidoglycan and its applications. Nat.Commun. 2017 PMID: 28425464