CMA

Name: CMA
Brand: Tocris Bioscience
SKU: 6677

Tocris Bioscience, part of Bio-Techne | Catalog # 6677

Citations (1)

COA / SDS

Murine-selective STING agonist

Key Product Details

Chemical Name:	9-Oxo-10(9H)-acridineacetic acid
Purity:	≥98%

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Technical Data
Citations

Biological Activity for CMA

CMA is a STING agonist; murine-selective (K_d = 3.5 μM). Triggers type I IFN response in murine macrophages, with no effect on human STING signaling.

Technical Data for CMA

Formula	C₁₅H₁₁NO₃
Storage	Store at +4°C
Purity	≥98%
CAS Number	38609-97-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CMA

Solubility

Soluble Soluble to 100 mM in DMSO

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References for CMA

References are publications that support the biological activity of the product.

Zhang et al. Rat and human STINGs profile similarly towards anticancer/antiviral compounds. Sci. Rep., 2015;5:18035 PMID: 26669264
Haag et al. Targeting STING with covalent small-molecule inhibitors. Nature, 2018;559:269 PMID: 29973723
Cavlar et al. Species-specific detection of the antiviral small-molecule compound CMA by STING. EMBO J., 2013;32:1440 PMID: 23604073

CMA

Tocris Bioscience, part of Bio-Techne | Catalog # 6677

Key Product Details

Biological Activity for CMA

Technical Data for CMA

Solubility for CMA

Dilution Calculator

Reconstitution Calculator

References for CMA

Product Documents for CMA

COA

Certificate of Analysis

SDS

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