Corticosterone

Name: Corticosterone
Brand: Tocris Bioscience
SKU: 3685
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 3685

(1)

Citations (30)

COA / SDS

Endogenous glucocorticoid

Key Product Details

Description:	Endogenous glucocorticoid
Chemical Name:	(11β)-11,21-Dihydroxypregn-4-ene-3,20-dione
Purity:	≥99% (HPLC)
Molecular Weight:	346.46

View Full Technical Details for Corticosterone

Technical Data
Citations / Reviews (1)

Biological Activity for Corticosterone

Corticosterone is an endogenous glucocorticoid that acts as an agonist at glucocorticoid and mineralocorticoid receptors.

Compound Libraries for Corticosterone

Corticosterone is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for Corticosterone

M. Wt	346.46
Formula	C₂₁H₃₀O₄
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	50-22-6
PubChem ID	5753
InChi Key	OMFXVFTZEKFJBZ-HJTSIMOOSA-N
Smiles	[H][C@@]23CCC1=CC(CC[C@@](C)1[C@]([H])2[C@@H](O)C[C@@]4(C)[C@]([H])3CC[C@@H]4[C@@](CO)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Corticosterone

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	34.65	100

Preparing Stock Solutions for Corticosterone

The following data is based on the product molecular weight 346.46.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.89 mL	14.43 mL	28.86 mL
5 mM	0.58 mL	2.89 mL	5.77 mL
10 mM	0.29 mL	1.44 mL	2.89 mL
50 mM	0.06 mL	0.29 mL	0.58 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Corticosterone

References are publications that support the biological activity of the product.

Lu International union of pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors. Pharmacol.Rev. 2006 PMID: 17132855