CYM 50260

Name: CYM 50260
Brand: Tocris Bioscience
SKU: 4677

Tocris Bioscience, part of Bio-Techne | Catalog # 4677

Citations (6)

COA / SDS

Potent and selective S1P4 agonist

Key Product Details

Description:	Potent and selective S1P₄ agonist
Chemical Name:	2-Chloro-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-(fluoromethyl)pyridine
Purity:	≥98% (HPLC)
Molecular Weight:	350.6

View Full Technical Details for CYM 50260

Technical Data
Citations

Biological Activity for CYM 50260

CYM 50260 is a potent sphingosine-1-phosphate receptor 4 (S1P₄) agonist (EC₅₀ = 45 nM). Displays no activity at other S1P receptor subtypes (S1P_1-3 and S1P₅) at concentrations up to 25 μM.

Compound Libraries for CYM 50260

CYM 50260 is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for CYM 50260

M. Wt	350.6
Formula	C₁₄H₁₁Cl₃FNO₂
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1355026-60-6
PubChem ID	44620894
InChi Key	FHPOTBQOUBMMCI-UHFFFAOYSA-N
Smiles	ClC1=CC(Cl)=C(OCCOC2=CC=C(CF)N=C2Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CYM 50260

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	35.06	100

Preparing Stock Solutions for CYM 50260

The following data is based on the product molecular weight 350.6.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.85 mL	14.26 mL	28.52 mL
5 mM	0.57 mL	2.85 mL	5.70 mL
10 mM	0.29 mL	1.43 mL	2.85 mL
50 mM	0.06 mL	0.29 mL	0.57 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for CYM 50260

References are publications that support the biological activity of the product.

Guerrero Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P₄-R) agonists. Bioorg.Med.Chem.Lett. 2011 PMID: 22119461