DH 97

Name: DH 97
Brand: Tocris Bioscience
SKU: 1218

Tocris Bioscience, part of Bio-Techne | Catalog # 1218

Citations (7)

COA / SDS

MT2 receptor antagonist

Key Product Details

Description:	MT₂ receptor antagonist
Chemical Name:	N-Pentanoyl-2-benzyltryptamine
Molecular Weight:	334.46

View Full Technical Details for DH 97

Technical Data
Citations

Biological Activity for DH 97

DH 97 is a relatively potent MT₂ melatonin receptor antagonist (pK_i value = 8.03), displaying 89- and 229-fold selectivity over MT₁ and GPR50 (melatonin-related orphan receptor) respectively.

Technical Data for DH 97

M. Wt	334.46
Formula	C₂₂H₂₆N₂O
Storage	Store at RT
CAS Number	220339-00-4
PubChem ID	3467177
InChi Key	HDOIPCLEKCEANF-UHFFFAOYSA-N
Smiles	CCCCC(=O)NCCC1=C(CC2=CC=CC=C2)NC2=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for DH 97

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO		100

Preparing Stock Solutions for DH 97

The following data is based on the product molecular weight 334.46.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.99 mL	14.95 mL	29.90 mL
5 mM	0.60 mL	2.99 mL	5.98 mL
10 mM	0.30 mL	1.49 mL	2.99 mL
50 mM	0.06 mL	0.30 mL	0.60 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for DH 97

References are publications that support the biological activity of the product.

Ting Molecular and pharmacological evidence for MT₁ melatonin receptor subtype in the tail artery of juvenile Wistar rats. Br.J.Pharmacol. 1999 PMID: 10433507
Teh and Sugden Comparison of the relationships of melatonin receptor agonists and antagonists; lengthening the N-acyl side chain has differing effects on potency on Xenopus melanophores. Naunyn Schmiedebergs Arch.Pharmacol. 1998 PMID: 9840420