Diclofenac sodium salt

Name: Diclofenac sodium salt
Brand: Tocris Bioscience
SKU: 4454

Tocris Bioscience, part of Bio-Techne | Catalog # 4454

Citations (2)

COA / SDS

Cyclooxygenase inhibitor; NSAID

Key Product Details

Chemical Name:	2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt
Purity:	≥99%

View Full Technical Details for Diclofenac sodium salt

Technical Data
Citations

Biological Activity for Diclofenac sodium salt

Diclofenac sodium salt is a nonsteroidal, anti-inflammatory drug (NSAID); inhibits COX-1 and COX-2 (IC₅₀ values are 0.075 μM for COX-1 and 0.038 μM for COX-2 in human whole blood assay).

Technical Data for Diclofenac sodium salt

Formula	C₁₄H₁₀Cl₂NNaO₂
Storage	Store at RT
Purity	≥99%
CAS Number	15307-79-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Diclofenac sodium salt

Solubility

Soluble Soluble to 50 mM in water and to 100 mM in DMSO

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References for Diclofenac sodium salt

References are publications that support the biological activity of the product.

Warner et al. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc.Natl.Acad.Sci.USA, 1999;96:7563 PMID: 10377455
Bort et al. Diclofenac toxicity to hepatocytes: a role for drug metabolism in cell toxicity. J.Pharmacol.Exp.Ther., 1998;288:65 PMID: 9862754
Laneuville et al. Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs. J.Pharmacol.Exp.Ther., 1994;271:927 PMID: 7965814

Diclofenac sodium salt

Tocris Bioscience, part of Bio-Techne | Catalog # 4454

Key Product Details

Biological Activity for Diclofenac sodium salt

Technical Data for Diclofenac sodium salt

Solubility for Diclofenac sodium salt

Dilution Calculator

Reconstitution Calculator

References for Diclofenac sodium salt

Product Documents for Diclofenac sodium salt

COA

Certificate of Analysis

SDS

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