(±)-CPSI 1306

Name: (±)-CPSI 1306
Brand: Tocris Bioscience
SKU: 4400

Tocris Bioscience, part of Bio-Techne | Catalog # 4400

Citations (2)

COA / SDS

Reported macrophage migration inhibitory factor (MIF) inhibitor

Key Product Details

Description:	Reported macrophage migration inhibitory factor (MIF) inhibitor
Chemical Name:	2-[3-(3-(2,4-Difluorophenyl)-4,5-dihydro-5-isoxazolyl]-1-(4-morpholinyl)ethanone
Purity:	≥98% (HPLC)
Molecular Weight:	310.3

View Full Technical Details for (±)-CPSI 1306

Technical Data
Citations

Biological Activity for (±)-CPSI 1306

(±)-CPSI 1306 is reported to be a macrophage inhibitory factor (MIF) inhibitor.

This product is racemic.

Compound Libraries for (±)-CPSI 1306

(±)-CPSI 1306 is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Antiviral Library. Find out more about compound libraries available from Tocris.

Technical Data for (±)-CPSI 1306

M. Wt	310.3
Formula	C₁₅H₁₆F₂N₂O₃
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1309793-47-2
PubChem ID	59723793
InChi Key	GUWOSEVHCSNYFK-UHFFFAOYSA-N
Smiles	FC(C=C2F)=CC=C2C1=NOC(CC(N3CCOCC3)=O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for (±)-CPSI 1306

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	31.03	100
	ethanol	3.1	10

Preparing Stock Solutions for (±)-CPSI 1306

The following data is based on the product molecular weight 310.3.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.22 mL	16.11 mL	32.23 mL
5 mM	0.64 mL	3.22 mL	6.45 mL
10 mM	0.32 mL	1.61 mL	3.22 mL
50 mM	0.06 mL	0.32 mL	0.64 mL

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References for (±)-CPSI 1306

References are publications that support the biological activity of the product.

Sanchez-Zamora Macrophage migration inhibitory factor is a therapeutic target in treatment of non-Ins-dependent diabetes mellitus. FASEB J. 2010 PMID: 20203087
Kithcart A small-molecule inhibitor of macrophage migration inhibitory factor for the treatment of inflammatory disease. FASEB J. 2010 PMID: 20624927