Domoic acid

Name: Domoic acid
Brand: Tocris Bioscience
SKU: 0269

Tocris Bioscience, part of Bio-Techne | Catalog # 0269

Citations (1)

COA / SDS

Potent and selective kainate agonist

Discontinued Product

0269 has been discontinued. View all Kainate Receptor Agonists products.

Key Product Details

Description:	Potent and selective kainate agonist
Chemical Name:	(2S,3S,4R,5'R)-2-Carboxy-4-(5'-carboxy-1'-methyl-1Z,3E-hexadienyl)-3-pyrrolidineacetic acid
Purity:	≥95% (HPLC)
Molecular Weight:	311.33

View Full Technical Details for Domoic acid

Technical Data
Citations

Biological Activity for Domoic acid

Domoic acid is a kainate receptor agonist. More potent and possibly more selective than kainate at kainate receptors, as demonstrated in electrophysiological studies.

Technical Data for Domoic acid

M. Wt	311.33
Formula	C₁₅H₂₁NO₆
Storage	Desiccate at -20°C
Purity	≥95% (HPLC)
CAS Number	14277-97-5
PubChem ID	5282253
InChi Key	VZFRNCSOCOPNDB-AOKDLOFSSA-N
Smiles	[H][C@](C)([C@](O)=O)/C=C/C=[C@@](C)\[C@H]1CN[C@H]([C@@](O)=O)[C@H]1CC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Domoic acid

References are publications that support the biological activity of the product.

Hampson and Manalo The activation of glutamate receptors by kainic acid and domoic acid. Nat.Toxins 1998 PMID: 10223631
Debonnel Domoic acid, the alleged 'mussel toxin', might produce its neurotoxic effect through kainate receptor activation: an electro-physiological study in rat dorsal hippocampus. Can.J.Physiol.Pharmacol. 1989 PMID: 2540893
Watkins Experiments with kainate and quisqualate agonists and antagonists in relation to the sub-classification of 'non-NMDA' receptors. Excitatory Amino Acids and Synaptic Plasticity. Ed
Agrawal and Evans The primary afferent depolarizing action of kainate in the rat. Br.J.Pharmacol. 1986 PMID: 3513882

Domoic acid

Tocris Bioscience, part of Bio-Techne | Catalog # 0269

Key Product Details

Biological Activity for Domoic acid

Technical Data for Domoic acid

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Domoic acid

Product Documents for Domoic acid

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

保持关注