DSPE-PEG 2000 Azide

Name: DSPE-PEG 2000 Azide
Brand: Tocris Bioscience
SKU: 8837

Tocris Bioscience, part of Bio-Techne | Catalog # 8837

COA / SDS

PEGylated DSPE with azide reactive group

Key Product Details

Description:	PEGylated DSPE with azide reactive group
Chemical Name:	1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-azido(polyethyleneglycol)-2000]
Purity:	≥90% (HPLC)

View Full Technical Details for DSPE-PEG 2000 Azide

Technical Data
Citations

Biological Activity for DSPE-PEG 2000 Azide

DSPE-PEG 2000 Azide is a functionalized phospholipid-polymer conjugate. It comprises a 1,2-distearoyl-sn-glycero-PE (DSPE) covalently coupled to a linear polyethylene glycol (Mr 2000) with an azide-terminated end for onward chemistry. It is commonly used to synthesize antibody-coupled liposomes and lipid nanoparticles. It has been used to make macrophage and EGFR antibody targeted LNPs using strain-promoted azide alkyne cycloaddition (SPAAC) click reaction.

Technical Data for DSPE-PEG 2000 Azide

Formula	(C₂H₄O)_nC₄₄H₈₄N₄O₁₀P.NH₄
Storage	Store at -20°C
Purity	≥90% (HPLC)
CAS Number	1938081-40-3
PubChem ID	168311704

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for DSPE-PEG 2000 Azide

Solubility

Soluble to 10mg/ml in ethanol and to 10mg/ml in chloroform

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References for DSPE-PEG 2000 Azide

References are publications that support the biological activity of the product.

Geisler EGFR-targeted ionizable lipid nanoparticles enhance in vivo mRNA delivery to the placenta. J.Control Release 2024 PMID: 38789090
Zhao Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. Proc.Natl.Acad.Sci.U.S.A. 2024 PMID: 38315853

DSPE-PEG 2000 Azide

Tocris Bioscience, part of Bio-Techne | Catalog # 8837

Key Product Details

Biological Activity for DSPE-PEG 2000 Azide

Technical Data for DSPE-PEG 2000 Azide

Solubility for DSPE-PEG 2000 Azide

Dilution Calculator

Reconstitution Calculator

References for DSPE-PEG 2000 Azide

Product Documents for DSPE-PEG 2000 Azide

COA

Certificate of Analysis

SDS

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