Dynamin inhibitory peptide, myristoylated (control)

Name: Dynamin inhibitory peptide, myristoylated (control)
Brand: Tocris Bioscience
SKU: 1776

Tocris Bioscience, part of Bio-Techne | Catalog # 1776

COA / SDS

Control peptide version of dynamin inhibitory peptide, myristoylated (Cat. No. 1775)

Discontinued Product

1776 has been discontinued. View all Dynamin Inhibitors products.

Key Product Details

Description:	Control peptide version of dynamin inhibitory peptide, myristoylated (Cat. No. 1775)
Molecular Weight:	1330.64

View Full Technical Details for Dynamin inhibitory peptide, myristoylated (control)

Technical Data
Citations

Biological Activity for Dynamin inhibitory peptide, myristoylated (control)

Dynamin inhibitory peptide, myristoylated (control) is a control peptide version of dynamin inhibitory peptide, myristoylated, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. In contrast to dynamin inhibitory peptide, has no significant effect on GABA_A receptor-mediated miniature IPSPs.

Active Analog also available.

Technical Data for Dynamin inhibitory peptide, myristoylated (control)

M. Wt	1330.64
Formula	C₆₁H₁₀₇N₁₉O₁₄
Single Letter Sequence	QPPASNPRVR (Modifications: Gln-1 = Myr-Gln, Arg-10 = C-terminal amide)
Storage	Desiccate at -20°C
PubChem ID	90488709
InChi Key	LRWOEJTUKITZIW-ZUSDHBTASA-N
Smiles	[H]N([C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)C(=O)CCCCCCCCCCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Dynamin inhibitory peptide, myristoylated (control)

References are publications that support the biological activity of the product.

Kittler Constitutive endocytosis of GABA_A receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 2000 PMID: 11050117
Nong Glycine binding primes NMDA receptor internalization. Nature 2003 PMID: 12646920
Grabs The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 1997 PMID: 9148966

Dynamin inhibitory peptide, myristoylated (control)

Tocris Bioscience, part of Bio-Techne | Catalog # 1776

Key Product Details

Biological Activity for Dynamin inhibitory peptide, myristoylated (control)

Technical Data for Dynamin inhibitory peptide, myristoylated (control)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Dynamin inhibitory peptide, myristoylated (control)

Product Documents for Dynamin inhibitory peptide, myristoylated (control)

COA

Certificate of Analysis

SDS

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