Ellipticine

Name: Ellipticine
Brand: Tocris Bioscience
SKU: 3357
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 3357

(1)

COA / SDS

Antitumor and intercalating agent; inhibits DNA topoisomerase II

Discontinued Product

3357 has been discontinued. View all DNA Topoisomerase Inhibitors products.

Key Product Details

Description:	Antitumor and intercalating agent; inhibits DNA topoisomerase II
Chemical Name:	5,11-Dimethyl-6H-pyrido[4,3-b]carbazole
Purity:	≥97% (HPLC)
Molecular Weight:	246.31

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Technical Data
Citations / Reviews (1)

Biological Activity for Ellipticine

Ellipticine is a naturally occurring plant alkaloid with antitumor activity. DNA intercalating agent; blocks DNA topoisomerase II activity. Prevents p53 phosphorylation in lung cancer cells.

Technical Data for Ellipticine

M. Wt	246.31
Formula	C₁₇H₁₄N₂
Storage	Store at +4°C
Purity	≥97% (HPLC)
CAS Number	519-23-3
PubChem ID	3213
InChi Key	CTSPAMFJBXKSOY-UHFFFAOYSA-N
Smiles	CC1=C4C(C=CN=C4)=C(C)C3=C1C2=C(N3)C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Ellipticine

References are publications that support the biological activity of the product.

Tewey Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II. J.Biol.Chem. 1984 PMID: 6086625
Ohashi Inhibition of p53 protein phosphorylation by 9-hydroxyellipticine: a possible anticancer mechanism. Jpn.J.Cancer Res. 1995 PMID: 7591958

Ellipticine

Tocris Bioscience, part of Bio-Techne | Catalog # 3357

Key Product Details

Biological Activity for Ellipticine

Technical Data for Ellipticine

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Ellipticine

Product Documents for Ellipticine

COA

Certificate of Analysis

SDS

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