ET 18-OCH₃

Biological Activity for ET 18-OCH₃

Technical Data for ET 18-OCH₃

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for ET 18-OCH₃

Preparing Stock Solutions for ET 18-OCH₃

The following data is based on the product molecular weight 523.73.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

References for ET 18-OCH₃

References are publications that support the biological activity of the product.

• Wong Phospholipase C and myosin light chain kinase inhibition define a common step in actin regulation during cytokinesis. BMC Cell Biol. 2007 PMID: 17509155
• Shimizu Roles of brain phosphatidylinositol-specific phospholipase C and diacylglycerol lipase in centrally administered histamine-induced adrenomedullary outflow in rats. Eur.J.Pharmacol. 2007 PMID: 17628524
• Aoki A radioreceptor binding assay for platelet-activating factor (PAF) using membranes from CHO cells expressing human PAF receptor. J.Immunol.Methods 1995 PMID: 7594622
• Powis Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues. Cancer Res. 1992 PMID: 1316230
• Briglia Edelfosine induced suicidal death of human erythrocytes. Cell.Physiol.Biochem. 2015 PMID: 26618532
• Mollinedo ET-18-OCH3 (edelfosine): a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor. Curr.Med.Chem. 2004 PMID: 15579006