ETP 45835 dihydrochloride

Name: ETP 45835 dihydrochloride
Brand: Tocris Bioscience
SKU: 5183

Tocris Bioscience, part of Bio-Techne | Catalog # 5183

Citations (1)

COA / SDS

Mnk1 and Mnk2 inhibitor

Discontinued Product

5183 has been discontinued. View all Mnk Inhibitors products.

Key Product Details

Description:	Mnk1 and Mnk2 inhibitor
Chemical Name:	4-[5-(4-Piperidinyl)-1H-pyrazol-3-yl]pyridine dihydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	301.21

View Full Technical Details for ETP 45835 dihydrochloride

Technical Data
Citations

Biological Activity for ETP 45835 dihydrochloride

ETP 45835 dihydrochloride is a Mnk2 and Mnk1 inhibitor (IC₅₀ values are 575 and 646 nM respectively). Exhibits selectivity against a panel of 24 protein kinases, including those upstream of Mnk1/2.

Technical Data for ETP 45835 dihydrochloride

M. Wt	301.21
Formula	C₁₃H₁₆N₄.2HCl
Storage	Desiccate at RT
Purity	≥99% (HPLC)
CAS Number	2136571-30-5
PubChem ID	71755761
InChi Key	ASYCTHXAPLLLSZ-UHFFFAOYSA-N
Smiles	C1(C2=CC(C3=CC=NC=C3)=NN2)CCNCC1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for ETP 45835 dihydrochloride

References are publications that support the biological activity of the product.

Oyarzabal Discovery of mitogen-activated protein kinase-interacting kinase 1 inhibitors by a comprehensive fragment-oriented virtual screening approach. J.Med.Chem. 2010 PMID: 20722422

ETP 45835 dihydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 5183

Key Product Details

Biological Activity for ETP 45835 dihydrochloride

Technical Data for ETP 45835 dihydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for ETP 45835 dihydrochloride

Product Documents for ETP 45835 dihydrochloride

COA

Certificate of Analysis

SDS

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