Fluvoxamine maleate

Name: Fluvoxamine maleate
Brand: Tocris Bioscience
SKU: 1033

Tocris Bioscience, part of Bio-Techne | Catalog # 1033

Citations (24)

COA / SDS

5-HT reuptake inhibitor

Key Product Details

Description:	5-HT reuptake inhibitor
Chemical Name:	(E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate
Purity:	≥99%
Molecular Weight:	434.41

View Full Technical Details for Fluvoxamine maleate

Technical Data
Citations

Biological Activity for Fluvoxamine maleate

Fluvoxamine maleate is a selective serotonin reuptake inhibitor; antidepressant. Binds to the human 5-HT transporter with a K_i of 1.6 nmol/l.

Technical Data for Fluvoxamine maleate

M. Wt	434.41
Formula	C₁₅H₂₁F₃N₂O₂.C₄H₄O₄
Storage	Desiccate at +4°C
Purity	≥99%
CAS Number	61718-82-9
PubChem ID	9560989
InChi Key	LFMYNZPAVPMEGP-PIDGMYBPSA-N
Smiles	OC(=O)\C=C/C(O)=O.COCCCC\C(C1=CC=C(C=C1)C(F)(F)F)=N/OCCN

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Fluvoxamine maleate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	4.34	10

Preparing Stock Solutions for Fluvoxamine maleate

The following data is based on the product molecular weight 434.41.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.02 mL	115.10 mL	230.20 mL
0.5 mM	4.60 mL	23.02 mL	46.04 mL
1 mM	2.30 mL	11.51 mL	23.02 mL
5 mM	0.46 mL	2.30 mL	4.60 mL

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References for Fluvoxamine maleate

References are publications that support the biological activity of the product.

Owens Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J.Pharmacol.Exp.Ther. 1997 PMID: 9400006
Classen Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor. Br.J.Pharmacol. 1977 PMID: 302726
Narita Interactions of selective serotonin reuptake inhibitors with subtypes of σ receptors in rat brain. Eur.J.Pharmacol. 1996 PMID: 8831113
Benfield and Ward Fluvoxamine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness. Drugs 1986 PMID: 3096686