Galanin (1-29) (rat, mouse)

Name: Galanin (1-29) (rat, mouse)
Brand: Tocris Bioscience
SKU: 2696

Tocris Bioscience, part of Bio-Techne | Catalog # 2696

Citations (3)

COA / SDS

Non-selective galanin receptor agonist

Key Product Details

Description:	Non-selective galanin receptor agonist
Purity:	≥95% (HPLC)
Molecular Weight:	3164.48

View Full Technical Details for Galanin (1-29) (rat, mouse)

Technical Data
Citations

Biological Activity for Galanin (1-29) (rat, mouse)

Galanin (1-29) (rat, mouse) is a non-selective galanin receptor agonist (K_i values are 0.98, 1.48 and 1.47 nM for GAL₁, GAL₂ and GAL₃ respectively). Anticonvulsant; prevents the occurrence of full kindled seizures in rats.

Technical Data for Galanin (1-29) (rat, mouse)

M. Wt	3164.48
Formula	C₁₄₁H₂₁₁N₄₃O₄₁
Single Letter Sequence	GWTLNSAGYLLGPHAIDNHRSFSDKHGLT (Modification: Thr-29 = C-terminal amide)
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	114547-31-8
PubChem ID	16201477
InChi Key	JHQDYHHNJBOXKP-UPNHMZDKSA-N
Smiles	[H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC=N1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Galanin (1-29) (rat, mouse)

Solubility

Soluble to 1mg/ml in water

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References for Galanin (1-29) (rat, mouse)

References are publications that support the biological activity of the product.

Mazarati Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: the effects of subtype-selective agonists and the role of G-protein-mediated signaling. J.Pharmacol.Exp.Ther. 2006 PMID: 16699066
Branchek Galanin receptor subtypes. TiPS.
Wang Cloning and expression characterization of a novel galanin receptor. J.Biol.Chem. 1997 PMID: 8995226