GM 6001

Biological Activity for GM 6001

Technical Data for GM 6001

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for GM 6001

References for GM 6001

References are publications that support the biological activity of the product.

• P Thornton, J Sevalle, MJ Deery, G Fraser, Y Zhou, S Ståhl, EH Franssen, RB Dodd, S Qamar, B Gomez Pere, LS Nicol, S Eketjäll, J Revell, C Jones, A Billinton, PH St George-, I Chessell, DC Crowther TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant EMBO Mol Med, 2017;0(0):. 2017 PMID: 28855301
• F Luo, AP Tran, L Xin, C Sanapala, BT Lang, J Silver, Y Yang Modulation of proteoglycan receptor PTP? enhances MMP-2 activity to promote recovery from multiple sclerosis Nat Commun, 2018;9(1):4126. 2018 PMID: 30297691
• KA Lahey, NJ Ronaghan, J Shang, SP Dion, A Désilets, R Leduc, WK MacNaughto Signaling pathways induced by serine proteases to increase intestinal epithelial barrier function PLoS ONE, 2017;12(7):e0180259. 2017 PMID: 28671992
• G Wisowski, EM Ko?ma, T Bielecki, A Pude?ko, K Olczyk Dermatan sulfate is a player in the transglutaminase 2 interaction network PLoS ONE, 2017;12(2):e0172263. 2017 PMID: 28199387
• C Sun, SB Feng, ZW Cao, JJ Bei, Q Chen, WB Zhao, XJ Xu, Z Zhou, ZP Yu, HY Hu Up-Regulated Expression of Matrix Metalloproteinases in Endothelial Cells Mediates Platelet Microvesicle-Induced Angiogenesis Cell. Physiol. Biochem., 2017;41(6):2319-2332. 2017 PMID: 28463834
• MA Schumacher, M Hedl, C Abraham, JK Bernard, PR Lozano, JJ Hsieh, D Almohazey, EB Bucar, S Punit, PJ Dempsey, MR Frey ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation Cell Death Dis, 2017;8(2):e2622. 2017 PMID: 28230865
• Shichi et al. Involvement of matrix metalloproteinase-mediated proteolysis of neural cell adhesion molecule in the development of cerebral ischemic neuronal damage. J.Pharmacol.Exp.Ther., 2011;338:701 PMID: 21602423
• Grobelny et al. Inhibition of skin fibroblast Col., thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids. Biochemistry, 1992;31:7152 PMID: 1322694
• Chao et al. Leptin stimulates endothelin-1 expression via extracellular signal-regulated kinase by epidermal growth factor receptor transactivation in rat aortic smooth muscle cells. Eur.J.Pharmacol., 2007;573:49 PMID: 17678888