Golgicide A

Name: Golgicide A
Brand: Tocris Bioscience
SKU: 3584

Tocris Bioscience, part of Bio-Techne | Catalog # 3584

Citations (11)

COA / SDS

Potent, selective and reversible inhibitor of GBF1 ArfGEF

Key Product Details

Chemical Name:	6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
Purity:	≥98%
Molecular Weight:	284.3 kDa

View Full Technical Details for Golgicide A

Technical Data
Citations

Biological Activity for Golgicide A

Golgicide A is a potent, specific and reversible inhibitor of Golgi BFA resistance factor 1 (GBF1), an ArfGEF, that decreases Arf1 activation in vivo. Arrests secretion of soluble and membrane-associated proteins at the endoplasmic reticulum-Golgi intermediate compartment. Causes disassembly and dispersal of the Golgi and trans-Golgi network.

Technical Data for Golgicide A

M. Wt	284.3 kDa
Formula	C₁₇H₁₄F₂N₂
Storage	Store at RT
Purity	≥98%
CAS Number	1139889-93-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Golgicide A

Solubility

Soluble Soluble to 50 mM in DMSO

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Golgicide A

References are publications that support the biological activity of the product.

Saenz et al. Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nature Chem.Biol., 2008;5:157