Grifolic acid

Name: Grifolic acid
Brand: Tocris Bioscience
SKU: 4581

Tocris Bioscience, part of Bio-Techne | Catalog # 4581

Citations (2)

COA / SDS

Selective partial FFA4 (GPR120) agonist

Key Product Details

Chemical Name:	2,4-Dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-benzoic acid
Purity:	≥98%

View Full Technical Details for Grifolic acid

Technical Data
Citations

Biological Activity for Grifolic acid

Grifolic acid is a selective partial FFA4 (GPR120) agonist. Induces ERK and [Ca²⁺]_i responses in cells expressing GPR120, but not those expressing GPR40.

Technical Data for Grifolic acid

Formula	C₂₃H₃₂O₄
Storage	Store at -20°C
Purity	≥98%
CAS Number	80557-12-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Grifolic acid

Solubility

Soluble Soluble to 100 mM in DMSO

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References for Grifolic acid

References are publications that support the biological activity of the product.

J Paillamanq, A Sanchez-Tu, EM Carmona, CL Treviño, C Sandoval, F Nualart, N Osses, JG Reyes Arachidonic acid triggers [Ca2+]i increases in rat round spermatids by a likely GPR activation, ERK signalling and ER/acidic compartments Ca2+ release PLoS ONE, 2017;12(2):e0172128. 2017 PMID: 28192519
Hara et al. Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch.Pharmacol., 2009;380:247 PMID: 19471906
Sun et al. Structure-activity relationships of GPR120 agonists based on a docking simulation. Mol.Pharmacol., 2010;78:804 PMID: 20685848

Grifolic acid

Tocris Bioscience, part of Bio-Techne | Catalog # 4581

Key Product Details

Biological Activity for Grifolic acid

Technical Data for Grifolic acid

Solubility for Grifolic acid

Dilution Calculator

Reconstitution Calculator

References for Grifolic acid

Product Documents for Grifolic acid

COA

Certificate of Analysis

SDS

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