GSK 9311 hydrochloride

Name: GSK 9311 hydrochloride
Brand: Tocris Bioscience
SKU: 6203

Tocris Bioscience, part of Bio-Techne | Catalog # 6203

COA / SDS

Negative control for GSK 6853

Key Product Details

Description:	Negative control for GSK 6853
Chemical Name:	N-[2,3-Dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-N-ethyl-2-methoxybenzamide hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	474

View Full Technical Details for GSK 9311 hydrochloride

Technical Data
Citations

Biological Activity for GSK 9311 hydrochloride

GSK 9311 hydrochloride is a negative control for GSK 6853 (Cat. No. 6198)

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the GSK 9311 probe summary on the SGC website.

Compound Libraries for GSK 9311 hydrochloride

GSK 9311 hydrochloride is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Epigenetics Library. Find out more about compound libraries available from Tocris.

Technical Data for GSK 9311 hydrochloride

M. Wt	474
Formula	C₂₄H₃₁N₅O₃.HCl
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	2253733-09-2
PubChem ID	121232406
InChi Key	WFXIHQFRQPGCCR-MRXNPFEDSA-N
Smiles	COC1=C(C(N(CC)C2=C(N3CCNC[C@H]3C)C=C4N(C(N(C4=C2)C)=O)C)=O)C=CC=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for GSK 9311 hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	47.4	100
	DMSO	47.4	100

Preparing Stock Solutions for GSK 9311 hydrochloride

The following data is based on the product molecular weight 474.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.11 mL	10.55 mL	21.10 mL
5 mM	0.42 mL	2.11 mL	4.22 mL
10 mM	0.21 mL	1.05 mL	2.11 mL
50 mM	0.04 mL	0.21 mL	0.42 mL

Molarity Calculator

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Reconstitution Calculator

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References for GSK 9311 hydrochloride

References are publications that support the biological activity of the product.

Bamborough GSK6853, a chemical probe for inhibition of the BRPF1 bromodomain. ACS Med.Chem.Lett. 2016 PMID: 27326325