Ionomycin calcium salt

Name: Ionomycin calcium salt
Brand: Tocris Bioscience
SKU: 1704
Rating: 5 (3 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 1704

(3)

Citations (29)

COA / SDS

Calcium ionophore

Key Product Details

Description:	Calcium ionophore
Chemical Name:	(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid calcium salt
Purity:	≥97% (HPLC)
Molecular Weight:	747.08

View Full Technical Details for Ionomycin calcium salt

Technical Data
Citations / Reviews (3)

Biological Activity for Ionomycin calcium salt

Ionomycin calcium salt is a calcium ionophore; more specific than A23187.

Free Acid also available.

Technical Data for Ionomycin calcium salt

M. Wt	747.08
Formula	C₄₁H₇₀O₉.Ca
Storage	Store at -20°C
Purity	≥97% (HPLC)
CAS Number	56092-82-1
PubChem ID	6446270
InChi Key	WKRWUYKLUMMAKG-WYGBAUISSA-L
Smiles	O=C([O-])CC[C@@H](C)C[C@H](C)C[C@H](C)C(/C=C([O-])/[C@H](C)C[C@@H](C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@]([C@]2([H])O[C@@]([C@H](O)C)(C)CC2)(C)O1)C)=O.[Ca+2]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Ionomycin calcium salt

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	ethanol	74.71	100
	DMSO	18.68	25 with gentle warming

Preparing Stock Solutions for Ionomycin calcium salt

The following data is based on the product molecular weight 747.08.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.34 mL	6.69 mL	13.39 mL
5 mM	0.27 mL	1.34 mL	2.68 mL
10 mM	0.13 mL	0.67 mL	1.34 mL
50 mM	0.03 mL	0.13 mL	0.27 mL

Molarity Calculator

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Reconstitution Calculator

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References for Ionomycin calcium salt

References are publications that support the biological activity of the product.

Kaufmann Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria. J.Biol.Chem. 1980 PMID: 6766939
Liu and Hermann Characterization of ionomycin as a calcium ionophore. J.Biol.Chem. 1978 PMID: 28319
Elzi Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils. Am.J.Physiol.Cell Physiol. 2001 PMID: 11401859