Ischemin sodium salt

Name: Ischemin sodium salt
Brand: Tocris Bioscience
SKU: 4695

Tocris Bioscience, part of Bio-Techne | Catalog # 4695

Citations (7)

COA / SDS

CBP inhibitor; cell permeable

Key Product Details

Chemical Name:	5-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid sodium salt
Purity:	≥99%

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Technical Data
Citations

Biological Activity for Ischemin sodium salt

Ischemin sodium salt is a CBP bromodomain inhibitor. Inhibits p53 interaction with CBP and decreases p53 transcriptional activity. Protects against Doxorubicin-induced apoptosis in cardiomyocytes in vitro. Cell permeable.

Technical Data for Ischemin sodium salt

Formula	C₁₅H₁₆N₃O₄SNa
Storage	Store at +4°C
Purity	≥99%

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Ischemin sodium salt

Solubility

Soluble Soluble to 100 mM in water and to 100 mM in DMSO

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References for Ischemin sodium salt

References are publications that support the biological activity of the product.

Borah et al. A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. Chem.Biol., 2011;18:531 PMID: 21513889

Ischemin sodium salt

Tocris Bioscience, part of Bio-Techne | Catalog # 4695

Key Product Details

Biological Activity for Ischemin sodium salt

Technical Data for Ischemin sodium salt

Solubility for Ischemin sodium salt

Dilution Calculator

Reconstitution Calculator

References for Ischemin sodium salt

Product Documents for Ischemin sodium salt

COA

Certificate of Analysis

SDS

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