JNJ 17203212

Biological Activity for JNJ 17203212

Technical Data for JNJ 17203212

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for JNJ 17203212

References for JNJ 17203212

References are publications that support the biological activity of the product.

• ME Hofmann, MC Andresen Dynasore blocks evoked release while augmenting spontaneous synaptic transmission from primary visceral afferents PLoS ONE, 2017;12(3):e0174915. 2017 PMID: 28358887
• Swanson et al. Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist. J.Med.Chem., 2005;48:1857 PMID: 15771431
• Ghilardi et al. Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain. J.Neurosci., 2005;25:3126 PMID: 15788769
• Bhattacharya et al. Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea pigs. J.Pharmacol.Exp.Ther., 2007;323:665 PMID: 17690251