L-Glutamic acid

Name: L-Glutamic acid
Brand: Tocris Bioscience
SKU: 0218
Rating: 5 (3 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 0218

(3)

Citations (73)

COA / SDS

Endogenous, non-selective glutamate receptor agonist

Key Product Details

Description:	Endogenous, non-selective glutamate receptor agonist
Chemical Name:	(S)-1-Aminopropane-1,3-dicarboxylic acid
Molecular Weight:	147.13

View Full Technical Details for L-Glutamic acid

Technical Data
Citations / Reviews (3)

Biological Activity for L-Glutamic acid

L-Glutamic acid is a the predominant excitatory transmitter in the mammalian central nervous system. L-Glutamic acid acts at ionotropic and metabotropic glutamate receptors.

MNI-caged-L-glutamate (Cat. No. 1490) also available.

Technical Data for L-Glutamic acid

M. Wt	147.13
Formula	C₅H₉NO₄
Storage	Store at RT
CAS Number	56-86-0
PubChem ID	33032
InChi Key	WHUUTDBJXJRKMK-VKHMYHEASA-N
Smiles	[H][C@@](CCC(O)=O)(N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for L-Glutamic acid

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	1eq. NaOH		100

Preparing Stock Solutions for L-Glutamic acid

The following data is based on the product molecular weight 147.13.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	6.80 mL	33.98 mL	67.97 mL
5 mM	1.36 mL	6.80 mL	13.59 mL
10 mM	0.68 mL	3.40 mL	6.80 mL
50 mM	0.14 mL	0.68 mL	1.36 mL

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Reconstitution Calculator

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References for L-Glutamic acid

References are publications that support the biological activity of the product.

Watkins and Evans Excitatory amino acid transmitters. Annu.Rev.Pharmacol.Toxicol. 1981 PMID: 6112965
Yang and Stockwell Ferroptosis: Death by lipid peroxidation. Trends Cell Biol. 2016 PMID: 26653790
Monaghan The excitatory amino acid receptors: their classes, pharmacology and distinct properties in the function of the central nervous system. Annu.Rev.Pharmacol.Toxicol. 1989 PMID: 2543272