Methysergide maleate

Name: Methysergide maleate
Brand: Tocris Bioscience
SKU: 1064

Tocris Bioscience, part of Bio-Techne | Catalog # 1064

Citations (18)

COA / SDS

5-HT1/5-HT2 antagonist

Key Product Details

Description:	5-HT₁/5-HT₂ antagonist
Chemical Name:	[8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8-carboxamide maleate
Purity:	≥99% (HPLC)
Molecular Weight:	469.54

View Full Technical Details for Methysergide maleate

Technical Data
Citations

Biological Activity for Methysergide maleate

Methysergide maleate is a mixed 5-HT₁/5-HT₂ receptor antagonist.

Technical Data for Methysergide maleate

M. Wt	469.54
Formula	C₂₁H₂₇N₃O₂.C₄H₄O₄
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	129-49-7
PubChem ID	5281073
InChi Key	LWYXFDXUMVEZKS-ZVFOLQIPSA-N
Smiles	OC(=O)\C=C/C(O)=O.[H][C@@]12CC3=CN(C)C4=CC=CC(=C34)C1=C[C@H](CN2C)C(=O)N[C@@H](CC)CO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Methysergide maleate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	4.7	10 with gentle warming

Preparing Stock Solutions for Methysergide maleate

The following data is based on the product molecular weight 469.54.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.30 mL	106.49 mL	212.97 mL
0.5 mM	4.26 mL	21.30 mL	42.59 mL
1 mM	2.13 mL	10.65 mL	21.30 mL
5 mM	0.43 mL	2.13 mL	4.26 mL

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Reconstitution Calculator

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References for Methysergide maleate

References are publications that support the biological activity of the product.

Hoyer VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol.Rev. 1994 PMID: 7938165