MNI-caged-NMDA

Name: MNI-caged-NMDA
Brand: Tocris Bioscience
SKU: 2224

Tocris Bioscience, part of Bio-Techne | Catalog # 2224

COA / SDS

Caged NMDA

Discontinued Product

2224 has been discontinued. View all Additional NMDA Receptor Compounds products.

Key Product Details

Description:	Caged NMDA
Alternative Names:	4-Methoxy-7-nitroindolinyl-caged N-methyl-D-aspartic acid
Chemical Name:	(R)-α-Methylamino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid
Purity:	≥99% (HPLC)
Molecular Weight:	323.3

View Full Technical Details for MNI-caged-NMDA

Technical Data
Citations

Biological Activity for MNI-caged-NMDA

MNI-caged-NMDA is a NMDA (Cat.No. 0114) caged with the photosensitive 4-methoxy-7-nitroindolinyl group. Stoichiometrically releases chirally pure NMDA. Suitable for uncaging with 300-380 nm excitation. Improved localization can be achieved by uncaging at 405 nm (with mM concentration of caged compound in the bath solution). Exhibits rapid uncaging rate relative to ionotropic glutamate receptor activation.

Licensing Information

Sold under license from the UK Medical Research Council

Technical Data for MNI-caged-NMDA

M. Wt	323.3
Formula	C₁₄H₁₇N₃O₆
Storage	Store at -20°C
Purity	≥99% (HPLC)
CAS Number	1227675-52-6
PubChem ID	57369294
InChi Key	MUCRWOILMOHLGD-SECBINFHSA-N
Smiles	O=C(C[C@H](C(O)=O)NC)N2C1=C([N+]([O-])=O)C=CC(OC)=C1CC2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for MNI-caged-NMDA

References are publications that support the biological activity of the product.

Palma-Cerda New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups. Neuropharmacology. 2012 PMID: 22609535