MRS 2211

Name: MRS 2211
Brand: Tocris Bioscience
SKU: 2402

Tocris Bioscience, part of Bio-Techne | Catalog # 2402

Citations (55)

COA / SDS

Competitive P2Y13 antagonist

Key Product Details

Description:	Competitive P2Y₁₃ antagonist
Chemical Name:	2-[(2-Chloro-5-nitrophenyl)azo]-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde disodium salt
Purity:	≥96% (HPLC)
Molecular Weight:	474.66

View Full Technical Details for MRS 2211

Technical Data
Citations

Biological Activity for MRS 2211

MRS 2211 is a competitive P2Y₁₃ receptor antagonist (pIC₅₀ = 5.97) that displays > 20-fold selectivity over P2Y₁ and P2Y₁₂ receptors.

Technical Data for MRS 2211

M. Wt	474.66
Formula	C₁₄H₁₀N₄O₈Na₂PCl
Storage	Desiccate at -20°C
Purity	≥96% (HPLC)
PubChem ID	57369297
InChi Key	VLNWYJFCKRYEJA-QIKYXUGXSA-L
Smiles	[Na+].[Na+].CC1=C(O)C(C=O)=C(COP([O-])([O-])=O)C(\N=N\C2=C(Cl)C=CC(=C2)[N+]([O-])=O)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for MRS 2211

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	33.23	70

Preparing Stock Solutions for MRS 2211

The following data is based on the product molecular weight 474.66.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.7 mM	3.01 mL	15.05 mL	30.10 mL
3.5 mM	0.60 mL	3.01 mL	6.02 mL
7 mM	0.30 mL	1.50 mL	3.01 mL
35 mM	0.06 mL	0.30 mL	0.60 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for MRS 2211

References are publications that support the biological activity of the product.

Kugelgen Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 2006 PMID: 16257449
Kim Synthesis of pyridoxal phosphate derivatives with antagonist activity at the P2Y₁₃ receptor. Biochem.Pharmacol. 2005 PMID: 15913566