Muristerone A

Name: Muristerone A
Brand: Tocris Bioscience
SKU: 3816

Tocris Bioscience, part of Bio-Techne | Catalog # 3816

COA / SDS

Stimulates Bcl-XL mRNA transcription; antiapoptotic

Discontinued Product

3816 has been discontinued. View all Additional Bcl-2 Family Compounds products.

Key Product Details

Description:	Stimulates Bcl-XL mRNA transcription; antiapoptotic
Chemical Name:	(2β,3β,5β,11α,22R)-2,3,5,11,14,20,22-Heptahydroxycholest-7-en-6-one
Purity:	≥97% (HPLC)
Molecular Weight:	496.63

View Full Technical Details for Muristerone A

Technical Data
Citations

Biological Activity for Muristerone A

Muristerone A is an ecdysone analog that acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.

Technical Data for Muristerone A

M. Wt	496.63
Formula	C₂₇H₄₄O₈
Storage	Store at -20°C
Purity	≥97% (HPLC)
CAS Number	38778-30-2
PubChem ID	122217
InChi Key	LRJUYAVTHIEHAI-LHBNDURVSA-N
Smiles	O[C@@H]1[C@H](O)C[C@](C(C=C3[C@@]([H])2[C@H](O)C[C@@]4(C)[C@](O)3CC[C@@]([H])4[C@](O)(C)[C@H](O)CCC(C)C)=O)(O)[C@]2(C)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Muristerone A

References are publications that support the biological activity of the product.

No Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proc.Natl.Acad.Sci.USA
Bosser and Zornig Agonists of an ecdysone-inducible mammalian expression system inhibit Fas-ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO. Cell Death Diff.
Patrick Muristerone A-induced nerve growth factor release from genetically engineered human dermal fibroblasts for peripheral nerve tissue engineering. Tissue Eng. 2001 PMID: 11429150

Muristerone A

Tocris Bioscience, part of Bio-Techne | Catalog # 3816

Key Product Details

Biological Activity for Muristerone A

Technical Data for Muristerone A

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Muristerone A

Product Documents for Muristerone A

COA

Certificate of Analysis

SDS

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