Nifedipine

Name: Nifedipine
Brand: Tocris Bioscience
SKU: 1075

Tocris Bioscience, part of Bio-Techne | Catalog # 1075

(5)

Citations (239)

COA / SDS

CaV1.x blocker

Key Product Details

Chemical Name:	1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester
Purity:	≥98%
Molecular Weight:	346.34 kDa

View Full Technical Details for Nifedipine

Technical Data
Citations / Reviews (5)

Biological Activity for Nifedipine

Nifedipine is a L-type calcium channel blocker.

Technical Data for Nifedipine

M. Wt	346.34 kDa
Formula	C₁₇H₁₈N₂O₆
Storage	Desiccate at +4°C
Purity	≥98%
CAS Number	21829-25-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Nifedipine

Solubility

Soluble Soluble to 100 mM in DMSO

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References for Nifedipine

References are publications that support the biological activity of the product.

Tung S, Hardy A, Wheeler M, Belsham D Serotonin (5-HT) activation of immortalized hypothalamic neuronal cells through the 5-HT1B serotonin receptor. Endocrinology, 2012;153(10):4862-73. 2012 PMID: 22919062
Fox JT, Sakamuru S, Huang R High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. 2012 PMID: 22431602
Mire E, Mezzera C, Leyva-Diaz E, Paternain AV, Squarzoni P, Bluy L, Castillo-Paterna M, Lopez MJ, Peregrin S, Tessier-Lavigne M, Garel S, Galceran J, Lerma J, Lopez-Bendito G Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth. Nat. Neurosci., 2012;15(8):1134-43. 2012 PMID: 22772332
Chen, Meng, Wan, Yehong, Ade, Kristen, Ting, Jonathan, Feng, Guoping, Calakos, Nicole Sapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity. J Neurosci, 2011;31(26):9563-73. 2011 PMID: 21715621
Stork and Cocks Pharmacological reactivity of human epicardial coronary arteries: phasic and tonic responses to vasoconstrictor agents differentiated by nifed. Br.J.Pharmacol., 1994;113:1093 PMID: 7889259

Product Documents for Nifedipine

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

SDS

⚠ WARNING: This product can expose you to chemicals including Nifedipine, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov