NK 252

Name: NK 252
Brand: Tocris Bioscience
SKU: 5293

Tocris Bioscience, part of Bio-Techne | Catalog # 5293

Citations (1)

COA / SDS

Nrf2 activator

Key Product Details

Chemical Name:	N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea
Purity:	≥98%

View Full Technical Details for NK 252

Technical Data
Citations

Biological Activity for NK 252

NK 252 is an Nrf2 activator; interacts with the Nrf2-binding site of Keap1. Downregulates the expression of fibrogenic genes and increases antioxidant effects in NASH rat models of liver disease.

Technical Data for NK 252

Formula	C₁₃H₁₁N₅O₃
Storage	Store at +4°C
Purity	≥98%
CAS Number	1414963-82-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for NK 252

Solubility

Soluble Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO

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References for NK 252

References are publications that support the biological activity of the product.

Shimozono et al. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol.Pharmacol., 2013;84:62 PMID: 23592516

NK 252

Tocris Bioscience, part of Bio-Techne | Catalog # 5293

Key Product Details

Biological Activity for NK 252

Technical Data for NK 252

Solubility for NK 252

Dilution Calculator

Reconstitution Calculator

References for NK 252

Product Documents for NK 252

COA

Certificate of Analysis

SDS

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