ONO 8130

Name: ONO 8130
Brand: Tocris Bioscience
SKU: 5406
Rating: 3 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 5406

(1)

Citations (4)

COA / SDS

EP1 receptor antagonist

Key Product Details

Chemical Name:	4-[[[2,3-Dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-indene-5yl]oxy]methyl]benzoic acid
Purity:	≥98%

View Full Technical Details for ONO 8130

Technical Data
Citations / Reviews (1)

Biological Activity for ONO 8130

ONO 8130 is an EP₁ receptor antagonist. Exhibits analgesic effect in a mouse model of cystitis. Orally bioavailable.

Technical Data for ONO 8130

Formula	C₂₅H₂₈N₂O₅S₂
Storage	Store at +4°C
Purity	≥98%
CAS Number	459841-96-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for ONO 8130

Solubility

Soluble Soluble to 100 mM in DMSO and to 20 mM in ethanol

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References for ONO 8130

References are publications that support the biological activity of the product.

Miki et al. ONO-8130, a selective prostanoid EP₁ receptor antagonist, relieves bladder pain in mice with cyclophosphamide-induced cystitis. Pain, 2011;152:1373 PMID: 21396778
Lipina et al. Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to cloz. in mouse models of schizophrenia. Psychopharmacology, 2005;179:54 PMID: 15759151

ONO 8130

Tocris Bioscience, part of Bio-Techne | Catalog # 5406

Key Product Details

Biological Activity for ONO 8130

Technical Data for ONO 8130

Solubility for ONO 8130

Dilution Calculator

Reconstitution Calculator

References for ONO 8130

Product Documents for ONO 8130

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

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