Oxcarbazepine

Name: Oxcarbazepine
Brand: Tocris Bioscience
SKU: 3864

Tocris Bioscience, part of Bio-Techne | Catalog # 3864

(1)

Citations (3)

COA / SDS

Anticonvulsant; inhibits Na+ channel activity

Key Product Details

Chemical Name:	10,11-Dihydro-10-oxo-5H-dibenzo(Z)[b,f]azepine-5-carboxamide
Purity:	≥98%
Molecular Weight:	252.27 kDa

View Full Technical Details for Oxcarbazepine

Technical Data
Citations / Reviews (1)

Biological Activity for Oxcarbazepine

Oxcarbazepine is an anticonvulsant; protects mice and rats against generalized tonic-clonic seizures induced by electroshock. Thought to act via inhibition of sodium channel activity.

Technical Data for Oxcarbazepine

M. Wt	252.27 kDa
Formula	C₁₅H₁₂N₂O₂
Storage	Store at RT
Purity	≥98%
CAS Number	28721-07-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Oxcarbazepine

Solubility

Soluble Soluble to 50 mM in DMSO

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References for Oxcarbazepine

References are publications that support the biological activity of the product.

Schmutz et al. Oxcarbazepine: preclinical anticonvulsant profile and putative mechanism of action. Epilepsia, 1994;35:S47 PMID: 8039471
Zheng et al. Oxcarbazepine, not its active metabolite, potentiates GABA_A activation and aggravates absence seizures. Epilepsia, 2009;50:83 PMID: 18717705
Ambrosio et al. Mechanism of action of carbamaz. and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024. Neurochem.Res., 2002;27:121 PMID: 11926264