Pelitinib

Biological Activity for Pelitinib

Technical Data for Pelitinib

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Pelitinib

References for Pelitinib

References are publications that support the biological activity of the product.

• Hegedüs Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: Implications for the emergence and reversal of cancer drug resistance Biochem. Pharmacol., 2012;84:260 PMID: 22548830
• Tyner et al. Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals. J.Clin.Invest., 2006;116:309 PMID: 16453019
• Torrance et al. Combinatorial chemoprevention of intestinal neoplasia. Nat.Med., 2000;6:1024 PMID: 10973323
• Nunes et al. Phosphorylation of extracellular signal-regulated kinase 1 and 2, protein kinase B, and signal transducer and activator of transcription 3 are differently inhibited by an epidermal growth factor receptor inhibitor, EKB-569, in tumor cells and normal human Mol.Cancer Ther., 2004;3:21 PMID: 14749472