PLP (139-151)

Name: PLP (139-151)
Brand: Tocris Bioscience
SKU: 2567

Tocris Bioscience, part of Bio-Techne | Catalog # 2567

Citations (2)

COA / SDS

Encephalitogenic myelin proteolipid fragment

Key Product Details

Purity:	≥95%
Molecular Weight:	1521.74 kDa

View Full Technical Details for PLP (139-151)

Technical Data
Citations

Biological Activity for PLP (139-151)

PLP (139-151) is a synthetic myelin proteolipid protein (PLP) fragment. Immunization with this peptide induces severe clinical and histological experimental allergic encephalomyelitis (EAE), an animal model of multiple sclerosis.

Technical Data for PLP (139-151)

M. Wt	1521.74 kDa
Formula	C₇₂H₁₀₄N₂₀O₁₇
Storage	Store at -20°C
Purity	≥95%
CAS Number	122018-58-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for PLP (139-151)

Solubility

Soluble Soluble to 2 mg/ml in water

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References for PLP (139-151)

References are publications that support the biological activity of the product.

Jana M, Mondal S, Gonzalez F, Pahan K Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-beta. J Biol Chem, 2012;287(41):34134-48. 2012 PMID: 22879602
Tuohy et al. Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. J.Immunol., 1989;142:1523 PMID: 2465343
Sobel et al. Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein. J.Neuropathol.Exp.Neurol., 1990;49:468 PMID: 2273404
Kuchroo et al. Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides. Pathobiology., 1991;59:305 PMID: 1716908