preQ1-biotin
Tocris Bioscience, part of Bio-Techne | Catalog # 7804
PreQ1 with biotin handle for RNA labeling and purification
Key Product Details
| Description: | PreQ1 with biotin handle for RNA labeling and purification |
| Chemical Name: | N-(6-(((2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)amino)hexyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide |
| Purity: | ≥95% (HPLC) |
| Molecular Weight: | 504.65 |
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E. coli TGT irreversibly exchanges a specific guanine in a DNA hairpin with preQ1-biotin. Schematic representation of preQ1-bitoin insertion into DNA. |
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E. coli TGT irreversibly exchanges a specific guanine in a DNA hairpin with preQ1-biotin. Urea-PAGE gel shift analysis of preQ1-biotin insertion. Modification is evidenced by an upward shift of the product band due to molecular weight increase. Lane 1 is unmodified DNA; lane 2 is preQ1-biotin modified DNA. |
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