Quipazine dimaleate

Name: Quipazine dimaleate
Brand: Tocris Bioscience
SKU: 0629

Tocris Bioscience, part of Bio-Techne | Catalog # 0629

Citations (3)

COA / SDS

5-HT3 agonist

Key Product Details

Chemical Name:	2-(1-Piperazinyl)quinoline dimaleate
Purity:	≥99%
Molecular Weight:	445.43 kDa

View Full Technical Details for Quipazine dimaleate

Technical Data
Citations

Biological Activity for Quipazine dimaleate

Quipazine dimaleate is a selective 5-HT₃ receptor agonist. Also displays antagonist activity at peripheral 5-HT₃ receptors. [³H]-Quipazine labels 5-HT₃ sites in the cortical membranes.

Technical Data for Quipazine dimaleate

M. Wt	445.43 kDa
Formula	C₁₃H₁₅N₃.2C₄H₄O₄
Storage	Store at RT
Purity	≥99%
CAS Number	150323-78-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Quipazine dimaleate

Solubility

Soluble Soluble to 100 mM in water

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References for Quipazine dimaleate

References are publications that support the biological activity of the product.

Fox JT, Sakamuru S, Huang R High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. 2012 PMID: 22431602
Ireland and Tyers Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve. Br.J.Pharmacol., 1987;90:229 PMID: 3814920
Peroutka and Hamik [³H]Quipazine labels 5-HT₃ recognition sites in rat cortical membranes. Eur.J.Pharmacol., 1988;148:297 PMID: 3378579
Sharif et al. Characteristics of 5-HT₃ binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [³H]-quipazine and [³H]-GR65630 binding. Br.J.Pharmacol., 1991;102:919 PMID: 1830236