Ro 90-7501

Name: Ro 90-7501
Brand: Tocris Bioscience
SKU: 2408

Tocris Bioscience, part of Bio-Techne | Catalog # 2408

Citations (2)

COA / SDS

Inhibitor of Aβ42 fibril formation

Key Product Details

Chemical Name:	2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine
Purity:	≥98%
Molecular Weight:	340.39 kDa

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Technical Data
Citations

Biological Activity for Ro 90-7501

Ro 90-7501 is an inhibitor of amyloid β42 (Aβ42) fibril assembly; reduces Aβ42-induced toxicity (EC₅₀ = 2 μM).

Technical Data for Ro 90-7501

M. Wt	340.39 kDa
Formula	C₂₀H₁₆N₆
Storage	Store at +4°C
Purity	≥98%
CAS Number	293762-45-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Ro 90-7501

Solubility

Soluble Soluble to 10 mM in 1eq. HCl and to 100 mM in DMSO

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References for Ro 90-7501

References are publications that support the biological activity of the product.

Bohrmann et al. Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates. J.Struct.Biol., 2000;130:232 PMID: 10940228