RU 24969 hemisuccinate

Name: RU 24969 hemisuccinate
Brand: Tocris Bioscience
SKU: 0912

Tocris Bioscience, part of Bio-Techne | Catalog # 0912

(1)

Citations (2)

COA / SDS

5-HT1A and 5-HT1B agonist

Key Product Details

Chemical Name:	5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate
Purity:	≥99%
Molecular Weight:	287.34 kDa

View Full Technical Details for RU 24969 hemisuccinate

Technical Data
Citations / Reviews (1)

Biological Activity for RU 24969 hemisuccinate

RU 24969 hemisuccinate is a potent 5-HT_1A/1B and moderate 5-HT_2C agonist that may also release 5-HT. Centrally active following systemic administration.

Technical Data for RU 24969 hemisuccinate

M. Wt	287.34 kDa
Formula	C₁₄H₁₆N₂O.½C₄H₆O₄
Storage	Store at RT
Purity	≥99%
CAS Number	66611-27-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for RU 24969 hemisuccinate

Solubility

Soluble Soluble to 50 mM in DMSO and to 30 mM in water

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References for RU 24969 hemisuccinate

References are publications that support the biological activity of the product.

Fox JT, Sakamuru S, Huang R High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. 2012 PMID: 22431602
Gudermann et al. Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine_1E-like serotonin receptor. Mol.Pharmacol., 1993;43:412 PMID: 8450834
Tomkins and O'Neill Effect of 5-HT_1B receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav., 2000;66:129 PMID: 10837852
Guillaume et al. Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antiDArgic properties. Eur.J.Med.Chem., 1987;22:33