(S)-(-)-Propranolol hydrochloride

Name: ( S )-(-)-Propranolol hydrochloride
Brand: Tocris Bioscience
SKU: 0834

Tocris Bioscience, part of Bio-Techne | Catalog # 0834

Citations (8)

COA / SDS

β antagonist. More active enantiomer of propranolol (Cat. No. 0624)

Key Product Details

Description:	β antagonist. More active enantiomer of propranolol (Cat. No. 0624)
Chemical Name:	(S)-(-)-1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	295.81

View Full Technical Details for (S)-(-)-Propranolol hydrochloride

Technical Data
Citations

Biological Activity for (S)-(-)-Propranolol hydrochloride

(S)-(-)-Propranolol hydrochloride is a more active enantiomer of the β-adrenoceptor antagonist propranolol.

Racemate, R-enantiomer and Glycol Metabolite also available.

Technical Data for (S)-(-)-Propranolol hydrochloride

M. Wt	295.81
Formula	C₁₆H₂₁NO₂.HCl
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	4199-10-4
PubChem ID	165193
InChi Key	ZMRUPTIKESYGQW-UQKRIMTDSA-N
Smiles	CC(C)NC[C@]([H])(O)COC2=CC=CC1=CC=CC=C12.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for (S)-(-)-Propranolol hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	5.92	20

Preparing Stock Solutions for (S)-(-)-Propranolol hydrochloride

The following data is based on the product molecular weight 295.81.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	16.90 mL	84.51 mL	169.03 mL
1 mM	3.38 mL	16.90 mL	33.81 mL
2 mM	1.69 mL	8.45 mL	16.90 mL
10 mM	0.34 mL	1.69 mL	3.38 mL

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References for (S)-(-)-Propranolol hydrochloride

References are publications that support the biological activity of the product.

Bond Metabolism of propra. (Inderal) a potent, specific β-adrenergic receptor blocking agent. Nature 1967 PMID: 6031788
Barrett The biological properties of the optical isomers of propra. and their effects on cardiac arrhythmias. Br.J.Pharmacol. 1968 PMID: 19108278