SC 51322

Name: SC 51322
Brand: Tocris Bioscience
SKU: 2791
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 2791

(1)

Citations (15)

COA / SDS

Potent EP1 receptor antagonist

Key Product Details

Chemical Name:	8-Chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]-dibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylic acid hydrazide
Purity:	≥98%
Molecular Weight:	457.93 kDa

View Full Technical Details for SC 51322

Technical Data
Citations / Reviews (1)

Biological Activity for SC 51322

SC 51322 is a potent EP₁ prostanoid receptor antagonist (K_i = 13.8 nM). Displays analgesic properties in vivo.

Technical Data for SC 51322

M. Wt	457.93 kDa
Formula	C₂₂H₂₀ClN₃O₄S
Storage	Store at -20°C
Purity	≥98%
CAS Number	146032-79-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for SC 51322

Solubility

Soluble Soluble to 100 mM in DMSO and to 25 mM in ethanol

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References for SC 51322

References are publications that support the biological activity of the product.

Durocher et al. A reporter gene assay for high-throughput screening of G-protein-coupled receptors stably or transiently expressed in HEK293 EBNA cells grown in suspension culture Anal.Biochem., 2000;284:316 PMID: 10964415
Hallinan et al. 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid,2-[3-[2-(furanylmethyl)thio]-1-oxopropyl]hydrazide (SC-51322): A potent PGE₂ antagonist and analgesic. Bioorg.Med.Chem.Lett., 1994;4:509