SCR7 pyrazine

Biological Activity for SCR7 pyrazine

Technical Data for SCR7 pyrazine

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for SCR7 pyrazine

References for SCR7 pyrazine

References are publications that support the biological activity of the product.

• Greco et al. Synthesis and structure determination of SCR7, a DNA ligase inhibitor Teterahedron Lett., 2016;57:3204
• Maruyama et al. Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining. Nat.Biotechnol., 2015;33:538 PMID: 25798939
• Greco et al. SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV. DNA Repair (Amst), 2016;43:18 PMID: 27235626
• Chu et al. Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells. Nat.Biotechnol., 2015;33:543 PMID: 25803306