SGC 3027N

Name: SGC 3027N
Brand: Tocris Bioscience
SKU: 6838

Tocris Bioscience, part of Bio-Techne | Catalog # 6838

COA / SDS

Negative control for SGC 3027 (Cat. No. 6825)

Key Product Details

Description:	Negative control for SGC 3027 (Cat. No. 6825)
Chemical Name:	N-(4-((((3aS,4S,6R,6aR)-6-(6-Amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl)thio)butyl)-N-((4'-chloro-[1,1'-biphenyl]-3-yl)methyl)-3-methyl-3-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide
Purity:	≥98% (HPLC)
Molecular Weight:	827.43

View Full Technical Details for SGC 3027N

Technical Data
Citations

Biological Activity for SGC 3027N

SGC 3027N is a negative control for SGC 3027 (Cat. No. 6825).

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the SGC 3027 probe summary on the SGC website.

Technical Data for SGC 3027N

M. Wt	827.43
Formula	C₄₄H₅₁ClN₆O₆S
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	2624313-14-8
InChi Key	FJBPSCVGHZASPG-LJVHFRCJSA-N
Smiles	ClC1=CC=C(C2=CC(CN(CCCCSC[C@H]3O[C@@H](N4C=NC5=C4N=CN=C5N)[C@H]6[C@@H]3OC(C)(C)O6)C(CC(C7=C(C)C(C(C)=C(C)C7=O)=O)(C)C)=O)=CC=C2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for SGC 3027N

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	82.74	100
	ethanol	8.27	10

Preparing Stock Solutions for SGC 3027N

The following data is based on the product molecular weight 827.43.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.21 mL	6.04 mL	12.09 mL
5 mM	0.24 mL	1.21 mL	2.42 mL
10 mM	0.12 mL	0.60 mL	1.21 mL
50 mM	0.02 mL	0.12 mL	0.24 mL

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Reconstitution Calculator

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References for SGC 3027N

References are publications that support the biological activity of the product.

Szewczy Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response. Nat.Commun. 2020 PMID: 32409666